Collapat® II

Collapat® II is a haemostatic bone substitute material available in fleece form. It is composed of a collagen matrix in which ceramised hydroxyapatite granules are dispersed. The synthetic hydroxyapatite granules give the material its osteoconductive properties. They are degraded over time. The collagen gives Collapat® II its strong haemostatic power. It is completely resorbable in a few weeks.

Features

resorbable bone substitute based on collagen and hydroxyapatite
strong haemostatic effect
synthetically derived pure hydroxyapatite
particle size of the hydroxyapatite granules 50-160 µm
bovine type I collagen
no immunogenicity

The Material

Collapat® II combines the two main bone components: hydroxyapatite and collagen.

The hydroxyapatite granules are synthetically derived and give the Collapat® II its osteoconductive properties. The collagen is extracted from calf skins originated from the United States of America and give the fleece its strong haemostatic effect. Thus Collapat® II is well indicated for filling strong bleeding bone defects, e.g. during spine surgeries like scoliosis treatment.

The manufacturing procedure comprises stages recognised to inactivate viruses and non-conventional transmissible agents such as prions. These treatments make it possible to ensure maximum microbiological safety for Collapat® II.

The Indications

Collapat® II is intended for the filling of aseptic, metaphyseal, cancellous bone defects. These bone defects might be caused by trauma or other genesis, e.g. a benign tumour, from surgery or congenital. Calcibon® is a one-time implant which stays in place until it will be biodegraded.

The Collapat® II fleece can comfortably be cut to the desired dimensions. It is ideally be mixed with blood, bone marrow aspirate or PRP (platelet rich plasma) from the GPS™ System. In contact with these substances Collapat® II adopts a paste-like consistency. As such it can perfectly be adapted to bone defects.

Depending on the indication accurate repositioning as well as fixation and stabilisation should be performed as if using autologous bone graft.

Well-tried indications for Collapat® II:

filling of strong bleeding bone defects, e.g. scoliosis treatment
reconstruction of the acetabulum after aseptic loosening
coverage of bone cysts after resection
filling material for cages

Current papers:

(1) Ries P. Collagenfleece as a bioimplant for orthopaedic surgery. Arch Orthop Trauma Surg 1992; 111: 66-69

(2) Katthagen BD. Knocheninduktion mit “Bone Morphogenetic Protein“ (BMP). Z Orthop 1987; 125: 559-566

(3) Katthagen BD, Mittelmeier H. Experimental animal investigation of bone regeneration with collagen-apatite. Arch Orthop Trauma Surg 1984; 103: 291-302

(4) Mittelmeier H, Katthagen BD. Klinische Erfahrung mit Collagen-Apatit-Implantation zur Knochenresorption. Z Orthop 1983; 121: 115-123

For further information about the products, health care professionals should contact their Biomet Europe representative or local office. Patients with questions about products are advised to contact their local surgeon.